Cincinnati skyline from the Ohio River, with a bridge in the foreground

Ohio River Cruise

At a glance

Duration:
9 Days
Start/End:
Louisville, KY to Pittsburgh, PA; or reverse
From:
$4,610
Time of Year:
July - August
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American Cruise Lines

Embark on a 9-day voyage along the storied waters of the Ohio River, a journey bridging lively river cities and tranquil small-town America. This route offers either a northbound cruise from Louisville, Kentucky to Pittsburgh, Pennsylvania, or the reverse, letting travelers choose their own adventure.

Your adventure begins in Louisville, where the city’s steep hills meet a historic waterfront, once a bustling hub of river commerce, now inviting you to explore its heritage and charm. The next morning, you’ll board your paddle-wheeler and ease into the gentle rhythm of river travel, greeted by a warm “Welcome Aboard,” and the first of many unforgettable sunsets along the water. Over the next days, the cruise alternates between scenic river travel and immersive stops ashore. In Madison, Indiana, wander among more than 130 preserved 19th-century buildings. History lives here, from Greek Revival and Victorian architecture to stories tied to the abolitionist movement. Stroll charming streets dotted with boutiques, galleries, and riverside views, imagining a quieter, gentler America. Then comes the visit to Cincinnati, Ohio, arriving under the dramatic arches of its river-spanning bridges. Known as the “Queen City,” Cincinnati blends industrial heritage with vibrant cultural flair. Onshore, you can explore world-class museums, theaters, botanical gardens, or catch a game at the historic ballpark. Don’t miss local culinary gems, whether savoring a bowl of Cincinnati-style chili or grabbing ice cream at a legendary shop founded in 1868.

Mid-voyage brings more time to drift lazily downriver, soak in the rolling hills, lush forests, gentle valleys, and the ever-changing riverside panorama. From lofty lounge decks or a private balcony, you’ll watch as the natural world unfolds in slow motion, an invitation to unwind, reflect, and enjoy the peaceful pulse of the Ohio. In Marietta, Ohio, dive into America’s early frontier history at the first permanent settlement in the Northwest Territory, a town where stately old buildings and storied streets echo with tales of early pioneers. It’s a chance to connect to a bygone era and appreciate the country’s roots. As the cruise draws toward its finale, you’ll approach Pittsburgh, the iconic “Steel City,” where the confluence of rivers, rolling hills, and a dramatic skyline mark the end of the journey. From the deck you’ll see the bridges and cityscape blend into the horizon. On shore, immerse yourself in Pittsburgh’s rich industrial past and its vibrant modern culture, a fitting end to an unforgettable river voyage.

Throughout your voyage, the onboard accommodations offer comfort and elegance, with stateroom choices ranging from private balconies to spacious veranda suites — each designed to make your river journey feel like a floating home. Dine in the glass-enclosed restaurant with panoramic views, relax in refined lounges, or take in the scenery from the sun deck’s putting green — all while the ship gently carries you along America’s heartland.

Ohio River Cruise Details

Day-to-Day Itinerary

Day 1: Louisville, KY

Nestled along the Ohio River, Louisville is a striking waterfront city that rises up the hillside with a rich history of commerce and celebration. Originally founded as a portage around the dangerous Falls of the Ohio—now submerged behind the Markland Dam—the town flourished as a hub of river trade. The city’s deep ties to the river are still celebrated today by the “Belle of Louisville,” a historic excursion boat that has been cruising the waters for over a century. After settling into your hotel, take some time to explore the city at your own pace.


Day 2: Day of Cruising

Step aboard your ship and kick off your journey with a warm Welcome Reception. Meet your fellow travelers while enjoying the scenic views as you cruise peacefully along the tranquil Ohio River this afternoon.


Day 3: Madison, IN

Nestled along the Ohio River, Madison is a charming, historic town renowned for its well-preserved 19th-century architecture. Its historic district, listed on the National Register of Historic Places, boasts over 130 buildings showcasing a blend of Greek Revival, Victorian, and Federal styles.

Madison’s rich history includes its crucial role in the Underground Railroad, with several local sites tied to the abolitionist movement. The town also hosts the Madison Regatta, one of the oldest hydroplane races in the U.S., celebrating its vibrant heritage.

Often called an outdoor museum of architecture, Madison’s downtown is a delightful mix of boutique shops, art galleries, and restaurants. Take a leisurely stroll through the area, admiring the town’s stunning natural beauty with sweeping views of the river and surrounding hills.


Day 4: Cincinnati, OH

As you arrive in Cincinnati, the dramatic bridges spanning the Ohio River offer a stunning introduction to this dynamic city. Known as the “Queen City” due to its early prominence in shipbuilding and trade, Cincinnati is a vibrant cultural hub.

Explore the city’s diverse attractions, including major sports teams, a delightful zoo, and the beautiful Krohn Conservatory, with its lush gardens. History and culture come to life at the National Underground Railroad Freedom Center, a Smithsonian Affiliate Museum, and the stunning St. Mary’s Cathedral Basilica.

Stroll through the charming streets, admiring the city’s eclectic architecture and stopping to savor local delights like Cincinnati’s famous Skyline Chili or a treat from Graeter’s Ice Cream, an institution since 1868.


Day 5: Day of Cruising

As you cruise along the grand Ohio River, experience the serene beauty of America’s heartland. Witness the gentle sweep of greenery along the banks, interspersed with quaint towns that can be seen from the top deck. Partake in a variety of onboard activities designed to enrich your journey, from historical presentations to lively discussions, each adding depth to the stunning vistas that unfold before you. Let the rhythm of the river carry you through landscapes steeped in history, offering a peaceful yet engaging backdrop to your exploration. Each mile traveled is a new chapter in the unfolding story of the Ohio River, inviting you to witness its quiet waves and enduring charm.


Day 6: Marietta, OH

Nestled at the confluence of the Muskingum and Ohio Rivers, this picturesque town is a treasure trove of history, featuring five National Register Historic Districts with buildings dating back to its founding in 1788. Explore the first settlement in the Northwest Territory on the north bank of the Ohio River, where significant events unfolded and were recently chronicled in The Pioneers, a compelling book by Pulitzer Prize-winning historian David McCullough. Uncover the rich stories that shaped this town and its vital role in America’s early frontier days.


Day 7: Day of Cruising

Enjoy a peaceful day cruising through the scenic Appalachian foothills, where lush landscapes and charming riverfront towns unfold before your eyes. Navigate through winding valleys, dense forests, serene lakes, and rolling hills, all showcasing nature’s pristine beauty. As you near Pittsburgh, the city’s iconic bridges and striking skyline emerge, nestled between the Allegheny and Monongahela rivers. The transition from the calm of rural life to the energy of the city is truly captivating, as Pittsburgh’s steel heritage seamlessly blends with its contemporary architecture, offering a stunning mix of past and present.


Day 8: Pittsburgh, PA

Our ship docks at the iconic point where the Allegheny and Monongahela Rivers meet, forming the majestic Ohio River. Pittsburgh, once a powerhouse of steel manufacturing, played a vital role in national and international trade, thriving in the 18th and 19th centuries. Discover stories of notable figures like Heinz, Carnegie, and other influential Americans who shaped this dynamic city.

As you cruise, enjoy the captivating and constantly evolving landscapes, just as early explorers did centuries ago. The rolling hills surrounding Pittsburgh offer a stunning backdrop, highlighting the city’s historic role as the gateway to the West for the young United States.


Day 9: Pittsburgh, PA

Savor a delicious breakfast on board as you prepare for your journey home. Take a moment to reflect on the unforgettable adventures and the new friendships you’ve made along the way.


Ohio River Cruise itinerary map

Dates & Rates

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Dates & Rates - Mississippi River - ACL - Ohio River Cruise
DateShipDirectionStandard WaterviewStandard BalconyDeluxe Balcony 2Deluxe BalconyDeluxe Balcony 1Premium BalconyVeranda SuiteGrand SuiteSingle WaterviewSingle Balcony
Thursday, July 2, 2026American HeritageLouisville to Pittsburgh$4,610$5,275$5,490$5,810$6,155Sold OutSold OutSold Out
Friday, July 3, 2026American MelodyPittsburgh to LouisvilleSold Out$5,810$6,155$7,295$9,345$6,705
Friday, July 10, 2026American HeritagePittsburgh to Louisville$4,610$5,275$5,490$5,810$6,155$7,295Sold Out$6,705
Friday, July 10, 2026American MelodyLouisville to PittsburghSold Out$5,810$6,155$7,295$9,345$6,705
Friday, July 17, 2026American HeritageLouisville to Pittsburgh$4,610$5,275$5,490$5,810$6,155$7,295Sold Out$6,705
Friday, July 17, 2026American MelodyPittsburgh to Louisville$5,275$5,810$6,155$7,295$9,345$6,705
Friday, July 24, 2026American HeritagePittsburgh to Louisville$4,610$5,275$5,490$5,810$6,155$7,295$6,065$6,705
Friday, July 24, 2026American MelodyLouisville to Pittsburgh$5,275$5,810$6,155$7,295$9,345$6,705
Friday, July 31, 2026American HeritageLouisville to Pittsburgh$4,610$5,275$5,490$5,810$6,155$7,295Sold Out$6,705
Friday, August 7, 2026American HeritagePittsburgh to LouisvilleSold Out$5,275$5,490$5,810$6,155$7,295Sold Out$6,705
Friday, August 14, 2026American HeritageLouisville to PittsburghSold Out$5,275$5,490$5,810$6,155Sold OutSold Out$6,705
Sunday, July 18, 2027American SymphonyLouisville to Pittsburgh$5,815$6,405$6,755$7,995$10,250$7,395
Monday, July 26, 2027American SymphonyPittsburgh to Louisville$5,815$6,405$6,755$7,995$10,250$7,395
Tuesday, August 3, 2027American SymphonyLouisville to Pittsburgh$5,815$6,405$6,755$7,995$10,250$7,395
Wednesday, August 11, 2027American SymphonyPittsburgh to Louisville$5,815$6,405$6,755$7,995$10,250$7,395

Dates and rates are effective the date the information was updated on this site. Dates and rates may have changed by the cruise line prior to an update here. Contact Sunstone Tours & Cruises for the latest dates & rates.

Prices subject to change.

Included

  • Cruise passage
  • All gourmet meals
  • Breakfast room service
  • Snacks
  • Cocktail hour each evening
  • Entertainment aboard the ship
  • Acclaimed enrichment program
  • Wi-Fi throughout the ship
  • Personalized service from a dedicated crew

Not Included

  • Air transport to/from embarkation/debarkation destinations
  • Most shore tours (unless otherwise noted)
  • Port charges and fees

Ships

ACL-American Heritage

American Heritage

The 150-passenger American Heritage offers an authentic paddlewheeler experience with all the comforts of home. Guests can enjoy large staterooms with private balconies, hotel-style bathrooms, and complimentary room service.

American Heritage Details …


American Melody

American Melody

The 195-passenger American Melody showcases all the beautiful modern styling and state-of-the-art technical features. The ship features the distinctive opening bow and retractable gangway.

American Melody Details …


The American Symphony

American Symphony

The 175-passenger American Symphony is the newest modern riverboat sailing the Mississippi River. She is one of the most sophisticated and elegant riverboats available on U.S. waters.

American Symphony Details …